If in doubt, ask your doctor or pharmacist about the safety of doubling up on certain pills, Cohen says.
"Don't be timid about asking your pharmacist a question," she advises. "They're drug information specialists and do their best to keep you safe."
Tip #2: Know the food rules for each drug
"It's usually OK if you eat something when you take your medication, but there are a few exceptions," says pharmacist Nancy Nkansah, Pharm. D., associate professor of clinical pharmacy at University of California, San Francisco.
For example, nonsteroidal anti-inflammatory drugs (NSAIDs) and many other pills, such as some antibiotics and vitamins, are better tolerated or absorbed when taken with food, she says.
But you may have to eliminate grapefruit, grapefruit juice and pomelos from your diet if you take certain drugs for anxiety, depression, cholesterol and other conditions, for example. These fruits contain chemicals called furanocoumarins, which can interfere with enzymes that help metabolize some medications and may cause your medication blood levels to get dangerously high, Nkansah says.
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