Animal research has shown that resveratrol increases the lifespan of worms, fruit flies and fish. In mice, it raises insulin sensitivity, decreases glucose levels and improves cardiac health, which suggests it may help prevent type 2 diabetes, heart disease and cancer.
Resveratrol also may influence sirtuins, proteins that keep cells healthy, and the Sirt1 (sirtuin1) gene, a gene that governs cellular longevity, says Leonard Guarente, Ph.D., an anti-aging specialist and MIT biology professor.
A 2006 Harvard study compared mice fed a standard diet, a high-calorie diet, or a high-calorie diet with resveratrol. Mice given resveratrol survived longer than both other groups, the researchers found.
Recommended dose: Most resveratrol supplements come from polygonum cuspidatum, a giant knotweed grown mainly in China and Japan. The actual resveratrol content varies from 50%-99%, depending on how it's processed.
Guarente recommends taking between 100 mg and 1 gram per day. But much smaller amounts may also be good for you, since red wine has less than 2 mg per glass.
Because of the publicity surrounding resveratrol products, they're vulnerable to scams. Buy from a company you trust, and avoid any that claim celebrity endorsements or offer a dubious "free trial."
[1][2][3]References
- ^ type 2 diabetes (www.lifescript.com)
- ^ heart disease (www.lifescript.com)
- ^ cancer (www.lifescript.com)
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